All-optical electrophysiology reveals the role of lateral inhibition in sensory processing in cortical layer 1
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Highlights:

 

•All-optical electrophysiology reveals synaptic excitation and inhibition, in vivo

•Whisker stimuli evoke concurrent excitation and inhibition in L1 interneurons

•Cholinergic inputs evoke winner-takes-all spiking in L1 interneurons

•Lateral inhibition within L1 governs whisker and cholinergic responses